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cd42b  (R&D Systems)


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    R&D Systems cd42b
    Cd42b, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 4 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/cd42b/Human+CD42b%2FGPIb+alpha+Antibody/pmc12888686-29-0-2
    Average 94 stars, based on 4 article reviews
    cd42b - by Bioz Stars, 2026-10
    94/100 stars

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    A Representative SEM image of PB. Scale bar: 200 nm. B Representative TEM image of PB. Scale bar: 200 nm. C Element mapping of PB. Scale bar: 100 nm. D TEM image of PB@PM. Scale bar: 50 nm. E Western blot analysis of CD41, <t>CD42b,</t> CD47, and GP6 expression in PM and PB@PM. Scale bar: 50 nm. F Fluorescence colocalization of PB and PM in PB@PM, and control represents a direct mixture of FITC-labeled PB (green) and Dil-labeled PM (red). Scale bar: 10 μm. G Typical ex vivo fluorescence images of major organs at 12 and 24 h after administration of Cy5.5-labeled PB (Sham mice; Control group), Cy5.5-labeled PB (MIRI mice; PB group), and Cy5.5-labeled PB@PM (MIRI mice; PB@PM group). H , I Quantitative analysis of the fluorescence intensities from separated hearts, livers, spleens, lungs, and kidneys in each group at 12 and 24 h, respectively ( n = 3 biologically independent replicates). Exact P- values from upper to lower: (12 h-heart) 8.70E-07, 9.50E-07, 0.8948; (24 h-heart) 0.0442; (12 h-liver) 0.6819; (24 h-liver) 0.9998; (12 h-spleen) 0.1353; (24 h-spleen) 0.9857; (12 h-lung) 0.0654; (24 h-lung) 0.0599; (12 h-kidney) 0.9741; (24 h-kidney) 0.8667. Data are expressed as mean ± SD. P- values were calculated by one-way ANOVA with Tukey’s correction. * P < 0.05, ** P < 0.01, *** P < 0.001, and ns implies P > 0.05. Source data are provided as a Source Data file.
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    A Representative SEM image of PB. Scale bar: 200 nm. B Representative TEM image of PB. Scale bar: 200 nm. C Element mapping of PB. Scale bar: 100 nm. D TEM image of PB@PM. Scale bar: 50 nm. E Western blot analysis of CD41, <t>CD42b,</t> CD47, and GP6 expression in PM and PB@PM. Scale bar: 50 nm. F Fluorescence colocalization of PB and PM in PB@PM, and control represents a direct mixture of FITC-labeled PB (green) and Dil-labeled PM (red). Scale bar: 10 μm. G Typical ex vivo fluorescence images of major organs at 12 and 24 h after administration of Cy5.5-labeled PB (Sham mice; Control group), Cy5.5-labeled PB (MIRI mice; PB group), and Cy5.5-labeled PB@PM (MIRI mice; PB@PM group). H , I Quantitative analysis of the fluorescence intensities from separated hearts, livers, spleens, lungs, and kidneys in each group at 12 and 24 h, respectively ( n = 3 biologically independent replicates). Exact P- values from upper to lower: (12 h-heart) 8.70E-07, 9.50E-07, 0.8948; (24 h-heart) 0.0442; (12 h-liver) 0.6819; (24 h-liver) 0.9998; (12 h-spleen) 0.1353; (24 h-spleen) 0.9857; (12 h-lung) 0.0654; (24 h-lung) 0.0599; (12 h-kidney) 0.9741; (24 h-kidney) 0.8667. Data are expressed as mean ± SD. P- values were calculated by one-way ANOVA with Tukey’s correction. * P < 0.05, ** P < 0.01, *** P < 0.001, and ns implies P > 0.05. Source data are provided as a Source Data file.
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    A Representative SEM image of PB. Scale bar: 200 nm. B Representative TEM image of PB. Scale bar: 200 nm. C Element mapping of PB. Scale bar: 100 nm. D TEM image of PB@PM. Scale bar: 50 nm. E Western blot analysis of CD41, <t>CD42b,</t> CD47, and GP6 expression in PM and PB@PM. Scale bar: 50 nm. F Fluorescence colocalization of PB and PM in PB@PM, and control represents a direct mixture of FITC-labeled PB (green) and Dil-labeled PM (red). Scale bar: 10 μm. G Typical ex vivo fluorescence images of major organs at 12 and 24 h after administration of Cy5.5-labeled PB (Sham mice; Control group), Cy5.5-labeled PB (MIRI mice; PB group), and Cy5.5-labeled PB@PM (MIRI mice; PB@PM group). H , I Quantitative analysis of the fluorescence intensities from separated hearts, livers, spleens, lungs, and kidneys in each group at 12 and 24 h, respectively ( n = 3 biologically independent replicates). Exact P- values from upper to lower: (12 h-heart) 8.70E-07, 9.50E-07, 0.8948; (24 h-heart) 0.0442; (12 h-liver) 0.6819; (24 h-liver) 0.9998; (12 h-spleen) 0.1353; (24 h-spleen) 0.9857; (12 h-lung) 0.0654; (24 h-lung) 0.0599; (12 h-kidney) 0.9741; (24 h-kidney) 0.8667. Data are expressed as mean ± SD. P- values were calculated by one-way ANOVA with Tukey’s correction. * P < 0.05, ** P < 0.01, *** P < 0.001, and ns implies P > 0.05. Source data are provided as a Source Data file.
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    A Representative SEM image of PB. Scale bar: 200 nm. B Representative TEM image of PB. Scale bar: 200 nm. C Element mapping of PB. Scale bar: 100 nm. D TEM image of PB@PM. Scale bar: 50 nm. E Western blot analysis of CD41, <t>CD42b,</t> CD47, and GP6 expression in PM and PB@PM. Scale bar: 50 nm. F Fluorescence colocalization of PB and PM in PB@PM, and control represents a direct mixture of FITC-labeled PB (green) and Dil-labeled PM (red). Scale bar: 10 μm. G Typical ex vivo fluorescence images of major organs at 12 and 24 h after administration of Cy5.5-labeled PB (Sham mice; Control group), Cy5.5-labeled PB (MIRI mice; PB group), and Cy5.5-labeled PB@PM (MIRI mice; PB@PM group). H , I Quantitative analysis of the fluorescence intensities from separated hearts, livers, spleens, lungs, and kidneys in each group at 12 and 24 h, respectively ( n = 3 biologically independent replicates). Exact P- values from upper to lower: (12 h-heart) 8.70E-07, 9.50E-07, 0.8948; (24 h-heart) 0.0442; (12 h-liver) 0.6819; (24 h-liver) 0.9998; (12 h-spleen) 0.1353; (24 h-spleen) 0.9857; (12 h-lung) 0.0654; (24 h-lung) 0.0599; (12 h-kidney) 0.9741; (24 h-kidney) 0.8667. Data are expressed as mean ± SD. P- values were calculated by one-way ANOVA with Tukey’s correction. * P < 0.05, ** P < 0.01, *** P < 0.001, and ns implies P > 0.05. Source data are provided as a Source Data file.
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    A Representative SEM image of PB. Scale bar: 200 nm. B Representative TEM image of PB. Scale bar: 200 nm. C Element mapping of PB. Scale bar: 100 nm. D TEM image of PB@PM. Scale bar: 50 nm. E Western blot analysis of CD41, <t>CD42b,</t> CD47, and GP6 expression in PM and PB@PM. Scale bar: 50 nm. F Fluorescence colocalization of PB and PM in PB@PM, and control represents a direct mixture of FITC-labeled PB (green) and Dil-labeled PM (red). Scale bar: 10 μm. G Typical ex vivo fluorescence images of major organs at 12 and 24 h after administration of Cy5.5-labeled PB (Sham mice; Control group), Cy5.5-labeled PB (MIRI mice; PB group), and Cy5.5-labeled PB@PM (MIRI mice; PB@PM group). H , I Quantitative analysis of the fluorescence intensities from separated hearts, livers, spleens, lungs, and kidneys in each group at 12 and 24 h, respectively ( n = 3 biologically independent replicates). Exact P- values from upper to lower: (12 h-heart) 8.70E-07, 9.50E-07, 0.8948; (24 h-heart) 0.0442; (12 h-liver) 0.6819; (24 h-liver) 0.9998; (12 h-spleen) 0.1353; (24 h-spleen) 0.9857; (12 h-lung) 0.0654; (24 h-lung) 0.0599; (12 h-kidney) 0.9741; (24 h-kidney) 0.8667. Data are expressed as mean ± SD. P- values were calculated by one-way ANOVA with Tukey’s correction. * P < 0.05, ** P < 0.01, *** P < 0.001, and ns implies P > 0.05. Source data are provided as a Source Data file.
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    Image Search Results


    A Representative SEM image of PB. Scale bar: 200 nm. B Representative TEM image of PB. Scale bar: 200 nm. C Element mapping of PB. Scale bar: 100 nm. D TEM image of PB@PM. Scale bar: 50 nm. E Western blot analysis of CD41, CD42b, CD47, and GP6 expression in PM and PB@PM. Scale bar: 50 nm. F Fluorescence colocalization of PB and PM in PB@PM, and control represents a direct mixture of FITC-labeled PB (green) and Dil-labeled PM (red). Scale bar: 10 μm. G Typical ex vivo fluorescence images of major organs at 12 and 24 h after administration of Cy5.5-labeled PB (Sham mice; Control group), Cy5.5-labeled PB (MIRI mice; PB group), and Cy5.5-labeled PB@PM (MIRI mice; PB@PM group). H , I Quantitative analysis of the fluorescence intensities from separated hearts, livers, spleens, lungs, and kidneys in each group at 12 and 24 h, respectively ( n = 3 biologically independent replicates). Exact P- values from upper to lower: (12 h-heart) 8.70E-07, 9.50E-07, 0.8948; (24 h-heart) 0.0442; (12 h-liver) 0.6819; (24 h-liver) 0.9998; (12 h-spleen) 0.1353; (24 h-spleen) 0.9857; (12 h-lung) 0.0654; (24 h-lung) 0.0599; (12 h-kidney) 0.9741; (24 h-kidney) 0.8667. Data are expressed as mean ± SD. P- values were calculated by one-way ANOVA with Tukey’s correction. * P < 0.05, ** P < 0.01, *** P < 0.001, and ns implies P > 0.05. Source data are provided as a Source Data file.

    Journal: Nature Communications

    Article Title: Prussian blue nanoparticles targeting multiple PANoptosome-mediated PANoptosis for myocardial ischemia-reperfusion injury therapy

    doi: 10.1038/s41467-026-70012-2

    Figure Lengend Snippet: A Representative SEM image of PB. Scale bar: 200 nm. B Representative TEM image of PB. Scale bar: 200 nm. C Element mapping of PB. Scale bar: 100 nm. D TEM image of PB@PM. Scale bar: 50 nm. E Western blot analysis of CD41, CD42b, CD47, and GP6 expression in PM and PB@PM. Scale bar: 50 nm. F Fluorescence colocalization of PB and PM in PB@PM, and control represents a direct mixture of FITC-labeled PB (green) and Dil-labeled PM (red). Scale bar: 10 μm. G Typical ex vivo fluorescence images of major organs at 12 and 24 h after administration of Cy5.5-labeled PB (Sham mice; Control group), Cy5.5-labeled PB (MIRI mice; PB group), and Cy5.5-labeled PB@PM (MIRI mice; PB@PM group). H , I Quantitative analysis of the fluorescence intensities from separated hearts, livers, spleens, lungs, and kidneys in each group at 12 and 24 h, respectively ( n = 3 biologically independent replicates). Exact P- values from upper to lower: (12 h-heart) 8.70E-07, 9.50E-07, 0.8948; (24 h-heart) 0.0442; (12 h-liver) 0.6819; (24 h-liver) 0.9998; (12 h-spleen) 0.1353; (24 h-spleen) 0.9857; (12 h-lung) 0.0654; (24 h-lung) 0.0599; (12 h-kidney) 0.9741; (24 h-kidney) 0.8667. Data are expressed as mean ± SD. P- values were calculated by one-way ANOVA with Tukey’s correction. * P < 0.05, ** P < 0.01, *** P < 0.001, and ns implies P > 0.05. Source data are provided as a Source Data file.

    Article Snippet: CD42b (A22277), CD47 (A21904), GP6 (A14999), Bcl-2 (A19693), TNF-α (A24214), IL-1β (A16288), IL-10 (A12255), ASC (A22046), FADD (A19838), MLKL (A26436), phospho-MLKL (AP1173), phospho-RIPK3 (AP1408), RIPK3 (A5431), phospho-RIPK1 (AP1230), RIPK1 (A7414), NLRP3 (A24294), cAMP (A1640), phospho-VASP (AP1510), VASP (A14217), AIM2 (A25252), and ZBP1 ( A22612 ) antibodies were purchased from ABclonal, China.

    Techniques: Western Blot, Expressing, Fluorescence, Control, Labeling, Ex Vivo